TRIM24 antibody (C-Term)
Quick Overview for TRIM24 antibody (C-Term) (ABIN7452099)
Target
See all TRIM24 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- Rabbit anti-TIF1 Alpha/TRIM24 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 1000 and C-term
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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Alternative Name
- TIF1 Alpha/TRIM24
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Background
- Background: TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.
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Gene ID
- 8805
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NCBI Accession
- NP_056989
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UniProt
- O15164
Target
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