UACA antibody (AA 1075-1125)

Catalog No. ABIN7452133

This Rabbit Polyclonal antibody specifically detects UACA in WB and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for UACA antibody (AA 1075-1125) (ABIN7452133)

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UACA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-UACA Antibody

Binding Specificity: AA 1075-1125

Purpose: Rabbit anti-UACA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1075 and 1125

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for UACA

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Alternative Name: UACA

Background: Background: UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats) was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Gene ID: 55075

NCBI Accession: NP_060473

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity