CUL9 antibody (C-Term)
Quick Overview for CUL9 antibody (C-Term) (ABIN7452200)
Target
See all CUL9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- Rabbit anti-PARC/H7-AP1 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 2475 and C-term
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: 1:20,000 - 1:30,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CUL9 (Cullin 9 (CUL9))
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Alternative Name
- PARC/H7-AP1
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Background
- Background: PARC is a member of the cullin family of proteins that act as scaffolds to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. PARC is highly homologous to and can form heterodimers with CUL7 (cullin 7). PARC/H7 interacts with p53 and was initially thought to have a role in the sequestration of p53 to the cytoplasm. Recent studies demonstrate that PARC may not influence p53 function or localization, but rather p53 may serve to regulate PARC/H7-AP1 function.
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Gene ID
- 23113
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NCBI Accession
- NP_055904
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UniProt
- Q8IWT3
Target
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