STK4 antibody (AA 375-425)

Catalog No. ABIN7452213

This anti-STK4 antibody is a Rabbit Polyclonal antibody detecting STK4 in WB and IP. Suitable for Human and Mouse.

Quick Overview for STK4 antibody (AA 375-425) (ABIN7452213)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-STK4 Antibody

Binding Specificity: AA 375-425

Purpose: Rabbit anti-MST1/STK4 Antibody, Affinity Purified

Predicted Reactivity: Monkey

Purification: Affinity Purified

Immunogen: between AA 375 and 425

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Alternative Name: MST1/STK4

Background: Background: MST1/STK4 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. MST1 can phosphorylate myelin basic protein and FOXO3. MST1 has been identified as a substrate of caspase and is required to mediate apoptosis in response to various apoptotic stimuli.

Gene ID: 6789

NCBI Accession: NP_006273

UniProt: Q13043

Pathways: Tube Formation