Myosin XVIIIA antibody (AA 300-350)

Catalog No. ABIN7452225

This anti-Myosin XVIIIA antibody is a Rabbit Polyclonal antibody detecting Myosin XVIIIA in IP. Suitable for Human.

Quick Overview for Myosin XVIIIA antibody (AA 300-350) (ABIN7452225)

Target: Myosin XVIIIA (MYO18A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin XVIIIA antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-Myosin XVIIIA Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-Myo18A/Myosin XVIIIA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452225 has not performed satisfactorily when used for WB of Myo18A/Myosin XVIIIA in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Myo18A/Myosin XVIIIA.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Myosin XVIIIA

Target: Myosin XVIIIA (MYO18A)

Alternative Name: Myo18A/Myosin XVIIIA

Background: Background: Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.

Gene ID: 399687

NCBI Accession: NP_510880

UniProt: Q92614