Coiled-Coil Domain Containing 88C (CCDC88C) (AA 1450-1500) antibody

Catalog No. ABIN7452244

Product Details

Target: Coiled-Coil Domain Containing 88C (CCDC88C)

Binding Specificity: AA 1450-1500

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-Daple Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1450 and 1500

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452244 has not performed satisfactorily when used for WB of Daple in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Daple.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: Coiled-Coil Domain Containing 88C (CCDC88C)

Alternative Name: Daple (CCDC88C Products)

Synonyms: 0610010D24Rik antibody, AV000935 antibody, AW324073 antibody, Daple antibody, mKIAA1509 antibody, RGD1307429 antibody, DAPLE antibody, HKRP2 antibody, KIAA1509 antibody, MGC160122 antibody, coiled-coil domain containing 88C antibody, Ccdc88c antibody, CCDC88C antibody

Background: Background: Daple (Dvl-associating protein with a high frequency of leucine residues) is a negative regulator of the canonical Wnt signaling pathway and acts downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization [taken from the Universal Protein Resource (UniProt) Q9P219].

Gene ID: 440193

NCBI Accession: NP_001073883

UniProt: Q9P219