SIRT2 antibody (AA 1-50)

Catalog No. ABIN7452250

This Rabbit Polyclonal antibody specifically detects SIRT2 in IP. It exhibits reactivity toward Human.

Quick Overview for SIRT2 antibody (AA 1-50) (ABIN7452250)

Target: SIRT2 (Sirtuin 2 (SIRT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT2 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-SIRT2 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Sirt2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. For endogenous Sirt2, nocodazole treatment and IP is required before blotting.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SIRT2

Target: SIRT2 (Sirtuin 2 (SIRT2))

Alternative Name: Sirt2

Background: Background: Sirt2 is one of seven members of the sirtuin family of proteins that are homologous to the yeast silent information regulator 2 (Sir2), a NAD+-dependent protein deacetylase that plays a role in lifespan in lower eukaryotes. The sirtuins are diverse in their cellular functions, and are important to the regulation of oxidative stress, and metabolism. Sirt2 is localized to the cytoplasm and functions as a NAD+-dependent tubulin and histone deacetylase. Its function is hypothesized to be important to the cell cycle.

Gene ID: 22933

NCBI Accession: NP_036369

UniProt: Q8IXJ6