DDX54 antibody (AA 800-850)
Quick Overview for DDX54 antibody (AA 800-850) (ABIN7452309)
Target
See all DDX54 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 800-850
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Purpose
- Rabbit anti-DDX54 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 800 and 850
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Isotype
- IgG
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Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-DDX54 antibody ABIN7453689.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- DDX54 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 54 (DDX54))
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Alternative Name
- DDX54
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Background
- Background: DDX54 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX54 has been shown to interact with nuclear hormone receptors in a hormone -dependent manner and repress their transcriptional activity.
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Gene ID
- 79039
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NCBI Accession
- NP_076977
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UniProt
- Q8TDD1
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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