DOCK1 antibody (AA 1715-1765)

Catalog No. ABIN7452310

This Rabbit Polyclonal antibody specifically detects DOCK1 in IP. It exhibits reactivity toward Human.

Quick Overview for DOCK1 antibody (AA 1715-1765) (ABIN7452310)

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-DOCK1 Antibody

Binding Specificity: AA 1715-1765

Purpose: Rabbit anti-DOCK180 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1715 and 1765

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-DOCK180 antibody ABIN7451742.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DOCK1

Target: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Alternative Name: DOCK180

Background: Background: DOCK80 is a non-conventional Rho-guanine nucleotide exchange factor (Rho-GEF) that functions to activate the small GTPases Rac and Cdc42. It is a member of the CZH (CDM-zizimin homology) family of proteins that contain two highly conserved domains, CZH1 and CZH2. Dock180 functions to activate Rac and regulate cell adhesion, cell spreading, migration and phagocytosis.

Gene ID: 1793

NCBI Accession: NP_001371

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor