DTX3L antibody (AA 75-125)

Catalog No. ABIN7452314

The Rabbit Polyclonal anti-DTX3L antibody is suitable to detect DTX3L in samples from Human. It has been validated for IP.

Quick Overview for DTX3L antibody (AA 75-125) (ABIN7452314)

Target: DTX3L (Deltex E3 ubiquitin ligase 3L (DTX3L))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTX3L antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-DTX3L Antibody

Binding Specificity: AA 75-125

Purpose: Rabbit anti-DTX3L/BBAP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 75 and 125

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-DTX3L antibody ABIN7449219.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DTX3L

Target: DTX3L (Deltex E3 ubiquitin ligase 3L (DTX3L))

Alternative Name: DTX3L/BBAP

Background: Background: The c-terminal of BBAP (B-lymphoma and BAL-binding protein) is highly homologous to the DTX family of proteins and like the DTX family of proteins, functions as an E3 ubiquitin ligase. BBAP associates with BAL1 a transcription factor linked to poor outcome in diffuse large B-cell lymphoma (DLBCL). BAL1 and BBAP expression has been shown to be coregulated, and BBAP has been found to regulate the subcellular localization of BAL1.

Gene ID: 151636

NCBI Accession: NP_612144

UniProt: Q8TDB6

Pathways: Notch Signaling