SETD1B antibody (AA 350-400)

Catalog No. ABIN7452567

The Rabbit Polyclonal anti-SETD1B antibody (ABIN7452567) specifically detects SETD1B in IP. The antibody is reactive with Human samples.

Quick Overview for SETD1B antibody (AA 350-400) (ABIN7452567)

Target: SETD1B (SET Domain Containing 1B (SETD1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD1B antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-SETD1B Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-hSET1B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 350 and 400

Isotype: IgG

Application Details

Application Notes:

IP: 2-10 μg/mg lysate

WB: Not recommended. ABIN7452567 has not performed satisfactorily when used for WB of hSet1B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of hSet1B.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SETD1B

Target: SETD1B (SET Domain Containing 1B (SETD1B))

Alternative Name: hSET1B

Background: Background: hSET1B is a histone methyltransferase that associates in a complex with the non-catalytic subunits CFP1, Rbbp5, Ash2, Wdr5, and Wdr82. These five non-catalytic subunits are also part of the Set1A complex. The SET1B complex has been shown to catalyze the tri-methylation of 'Lys-4' on histone H3. SET1B has been shown to localize to sites independent of SET1A complexes indicating non-redundant functions between SET1B and SET1A complexes.

Gene ID: 23067

NCBI Accession: NP_055863

UniProt: Q9UPS6