Aprataxin antibody (AA 100-150)

Catalog No. ABIN7452694

This Rabbit Polyclonal antibody specifically detects Aprataxin in WB and IP. It exhibits reactivity toward Human.

Quick Overview for Aprataxin antibody (AA 100-150) (ABIN7452694)

Target: Aprataxin (APTX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Aprataxin Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-Aprataxin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 100 and 150

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: Aprataxin

Background: Background: The Aprataxin gene was identified by linkage analysis as the defective gene in the neurogenerative disorder ataxia with oculomotor apraxia type 1 (AOA1) which is characterized by cerebellar ataxia, peripheral neuropathy, and hypoalbuminemia. Aprataxin functions in the DNA damage response and is involved in single-strand and double-strand break repair, and base excision repair.

Gene ID: 54840

NCBI Accession: NP_001182181

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding