FANCE antibody (AA 500-550)

Catalog No. ABIN7452729

The Rabbit Polyclonal anti-FANCE antibody (ABIN7452729) specifically detects FANCE in IP. The antibody is reactive with Human samples.

Quick Overview for FANCE antibody (AA 500-550) (ABIN7452729)

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCE antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-FANCE Antibody

Binding Specificity: AA 500-550

Purpose: Rabbit anti-FANCE Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 500 and 550

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-FANCE antibody ABIN7452702.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Alternative Name: FANCE

Background: Background: FANCE (Fanconi anemia, complementation group E) is a protein involved in DNA repair. Defects in FANCE are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCE gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. FANCE has been shown to mediate the interaction between FANCC and FANCD2.

Gene ID: 2178

NCBI Accession: NP_068741

UniProt: Q9HB96

Pathways: DNA Damage Repair