FANCE antibody (AA 500-550)
Quick Overview for FANCE antibody (AA 500-550) (ABIN7452729)
Target
See all FANCE AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 500-550
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Purpose
- Rabbit anti-FANCE Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 500 and 550
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Isotype
- IgG
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Application Notes
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IP: 5 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-FANCE antibody ABIN7452702.
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- FANCE (Fanconi Anemia, Complementation Group E (FANCE))
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Alternative Name
- FANCE
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Background
- Background: FANCE (Fanconi anemia, complementation group E) is a protein involved in DNA repair. Defects in FANCE are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCE gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. FANCE has been shown to mediate the interaction between FANCC and FANCD2.
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Gene ID
- 2178
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NCBI Accession
- NP_068741
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UniProt
- Q9HB96
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Pathways
- DNA Damage Repair
Target
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