EIF2AK1 antibody (AA 525-575)

Catalog No. ABIN7452780

This anti-EIF2AK1 antibody is a Rabbit Polyclonal antibody detecting EIF2AK1 in IP. Suitable for Human.

Quick Overview for EIF2AK1 antibody (AA 525-575) (ABIN7452780)

Target: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2AK1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-EIF2AK1 Antibody

Binding Specificity: AA 525-575

Purpose: Rabbit anti-EIF2AK1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 525 and 575

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 15 μg/mg lysate

WB: Not recommended. ABIN7452790 has not performed satisfactorily when used for WB of EIF2AK1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of EIF2AK1.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EIF2AK1

Target: EIF2AK1 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 1 (EIF2AK1))

Alternative Name: EIF2AK1

Background: Background: Eukaryotic translation initiation factor 2-alpha kinase 1 (EIF2AK1) is also known as Heme-regulated inhibitor (HRI). EIF2AK1 is regulated and inactivated by Hemin. EIF2AK1 Mediates down-regulation of protein synthesis in response to various stress conditions by the phosphorylation of eIF-2alpha at 'Ser-48' and 'Ser-51'.

Gene ID: 27102

NCBI Accession: NP_055228

UniProt: Q9BQI3

Pathways: Hepatitis C