EFTUD1 antibody (AA 700-750)

Catalog No. ABIN7452817

This Rabbit Polyclonal antibody specifically detects EFTUD1 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for EFTUD1 antibody (AA 700-750) (ABIN7452817)

Target: EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFTUD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-EFTUD1 Antibody

Binding Specificity: AA 700-750

Purpose: Rabbit anti-EFTUD1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 700 and 750

Isotype: IgG

Application Details

Application Notes:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EFTUD1

Target: EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))

Alternative Name: EFTUD1

Background: Background: EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits. [taken from the Universal Protein Resource (UniProt) Q7Z2Z2].

Gene ID: 79631

UniProt: Q7Z2Z2

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly