FBXO31 antibody (AA 489-539)

Catalog No. ABIN7452935

Product Details anti-FBXO31 Antibody

Target: FBXO31 (F-Box Protein 31 (FBXO31))

Binding Specificity: AA 489-539

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO31 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-FBXO31 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 489 and 539

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FBXO31

Target: FBXO31 (F-Box Protein 31 (FBXO31))

Alternative Name: FBXO31 (FBXO31 Products)

Background: Background: FBXO31 (F-box only protein 31) is a member of the F-box family of proteins and a component of the SCF (SKP1-cullin-F-box) protein ligase complex. FBXO31 is a candidate tumor suppressor protein that displays loss of heterozygosity in breast, ovarian, hepatocellular, and prostate cancers. In the DNA damage response FBXO31 has been found to mediate the degradation of cyclin D1 via a proteasome-directed pathway.

Gene ID: 79791

NCBI Accession: NP_079011

UniProt: Q5XUX0