Thimet Oligopeptidase 1 antibody (AA 25-75)

Catalog No. ABIN7453016

The Rabbit Polyclonal anti-Thimet Oligopeptidase 1 antibody has been validated for WB. It is suitable to detect Thimet Oligopeptidase 1 in samples from Human and Mouse.

Quick Overview for Thimet Oligopeptidase 1 antibody (AA 25-75) (ABIN7453016)

Target: Thimet Oligopeptidase 1 (THOP1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thimet Oligopeptidase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Thimet Oligopeptidase 1 Antibody

Binding Specificity: AA 25-75

Purpose: Rabbit anti-THOP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Thimet Oligopeptidase 1

Target: Thimet Oligopeptidase 1 (THOP1)

Alternative Name: THOP1

Background: Background: Thimet oligopeptidase (THOP1) is a kininase that uses zinc as a cofactor. THOP1 cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. THOP1 also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides [taken from NCBI Entrez Gene (Gene ID: 7064)].

Gene ID: 7064

UniProt: P52888