ATXN7 antibody (AA 842-892)

Catalog No. ABIN7453039

This Rabbit Polyclonal antibody specifically detects ATXN7 in WB. It exhibits reactivity toward Human.

Quick Overview for ATXN7 antibody (AA 842-892) (ABIN7453039)

Target: ATXN7 (Ataxin 7 (ATXN7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATXN7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATXN7 Antibody

Binding Specificity: AA 842-892

Purpose: Rabbit anti-Ataxin-7 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 842 and 892

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ATXN7

Target: ATXN7 (Ataxin 7 (ATXN7))

Alternative Name: Ataxin-7

Background: Background: Defects in ATXN7 are the cause of spinocerebellar ataxia type 7 (SCA7) also known as olivopontocerebellar atrophy III (OPCA III or OPCA3) or olivopontocerebellar atrophy with retinal degeneration. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. Ataxin 7 acts as a component of the STAGA transcription coactivator-HAT complex. It mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation [taken from the Universal Protein Resource (UniProt) O15265].

Gene ID: 6314

NCBI Accession: NP_000324

UniProt: O15265