IDE antibody (AA 275-326)

Catalog No. ABIN7453106

The Rabbit Polyclonal anti-IDE antibody has been validated for WB. It is suitable to detect IDE in samples from Human.

Quick Overview for IDE antibody (AA 275-326) (ABIN7453106)

Target: IDE (Insulin-Degrading Enzyme (IDE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDE antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IDE Antibody

Binding Specificity: AA 275-326

Purpose: Rabbit anti-IDE Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 275 and 326

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IDE

Target: IDE (Insulin-Degrading Enzyme (IDE))

Alternative Name: IDE

Background: Background: Insulin-degrading enzyme (IDE) is a metalloendopeptidase that plays a primary role in the regulated degradation of insulin. In the cell, IDE is found mostly in the soluble cytosolic fraction, and small amounts exist in the plasma membrane, endosomes, and peroxisomes, however the highest relative concentration is found in the peroxisomes. IDE is proposed to be a multifunctional enzyme since it is also present in non-insulin sensitive cells. Other substrates of IDE include glucagon, IGF-II, atrial natriuretic factor, and TGF-alpha.

Gene ID: 3416

NCBI Accession: NP_004960

UniProt: P14735

Pathways: SARS-CoV-2 Protein Interactome