ITGA2 antibody (AA 25-75)

Catalog No. ABIN7453111

This Rabbit Polyclonal antibody specifically detects ITGA2 in WB. It exhibits reactivity toward Human.

Quick Overview for ITGA2 antibody (AA 25-75) (ABIN7453111)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITGA2 Antibody

Binding Specificity: AA 25-75

Purpose: Rabbit anti-ITGA2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 25 and 75

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2/CD49B/Integrin alpha-2

Background: Background: Integrin alpha-2 is product of the gene ITGA2 (aka CD49B). Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. This receptor mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia [taken from NCBI Entrez Gene (Gene ID: 3673) and UniProtKB (Entry: P17301)].

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex