PCGF2 antibody (AA 125-175)

Catalog No. ABIN7453132

This Rabbit Polyclonal antibody specifically detects PCGF2 in WB. It exhibits reactivity toward Human.

Quick Overview for PCGF2 antibody (AA 125-175) (ABIN7453132)

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCGF2 Antibody

Binding Specificity: AA 125-175

Purpose: Rabbit anti-Mel-18 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 125 and 175

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Alternative Name: Mel-18

Background: Background: Mel18 is a transcriptional repressor and binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel-18 is a component of a polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Mel-18 has tumor suppressor activity. Mel-18 plays a role in control of cell proliferation and/or neural cell development, and also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. [taken from the Universal Protein Resource (UniProt) P35227].

Gene ID: 7703

NCBI Accession: NP_009075

UniProt: P35227

Pathways: Chromatin Binding