Treslin antibody (AA 975-1025)

Catalog No. ABIN7453283

Product Details anti-Treslin Antibody

Target: Treslin

Binding Specificity: AA 975-1025

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Treslin antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-Treslin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 975 and 1025

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Treslin

Target: Treslin

Abstract: Treslin Products

Synonyms: C15orf42 antibody, SLD3 antibody, Treslin antibody, 5730590G19Rik antibody, BC028450 antibody, Lrrk1 antibody, c15orf42 antibody, TOPBP1 interacting checkpoint and replication regulator antibody, TopBP1-interacting, checkpoint, and replication regulator antibody, TOPBP1-interacting checkpoint and replication regulator antibody, TOPBP1-interacting checkpoint and replication regulator L homeolog antibody, TICRR antibody, ticrr antibody, Ticrr antibody, ticrr.L antibody

Background: Background: Treslin is a regulator of DNA replication and S/M and G2/M checkpoints. Treslin regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Treslin is required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC) and for the prevention of mitotic entry after treatment with ionizing radiation [taken from the Universal Protein Resource (UniProt) Q7Z2Z1].

Gene ID: 90381

NCBI Accession: NP_689472

UniProt: Q7Z2Z1