FANCA antibody (AA 1405-1455)
Quick Overview for FANCA antibody (AA 1405-1455) (ABIN7453316)
Target
See all FANCA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1405-1455
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Purpose
- Rabbit anti-FANCA Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- Between AA 1405 and 1455
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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Alternative Name
- FANCA
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Background
- Background: FANCA (Fanconi anemia, complementation group A) is a protein involved in DNA repair. Defects in FANCA are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCA gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. The FANC members are not homologous proteins but are related by their assembly into a common nuclear complex.
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Gene ID
- 2175
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NCBI Accession
- NP_000126
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UniProt
- O15360
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Pathways
- DNA Damage Repair
Target
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