SMC2 antibody (C-Term)

Catalog No. ABIN7453335

The Rabbit Polyclonal anti-SMC2 antibody (ABIN7453335) specifically detects SMC2 in WB, ICC and IP. The antibody is reactive with Human samples.

Quick Overview for SMC2 antibody (C-Term) (ABIN7453335)

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-SMC2 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-SMC2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1150 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

ICC: 1:200 - 1:400

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2

Background: Background: Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.

Gene ID: 10592

NCBI Accession: NP_006435

UniProt: O95347