RIF1 antibody (AA 1-50)

Catalog No. ABIN7453551

This anti-RIF1 antibody is a Rabbit Polyclonal antibody detecting RIF1 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for RIF1 antibody (AA 1-50) (ABIN7453551)

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-RIF1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-RIF1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-RIF1 Antibodies or ABIN7453412.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RIF1

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Alternative Name: RIF1

Background: Background: RAP1 interacting factor (RIF1) localizes to dysfunctional telomeres and functions in the S-phase checkpoint. In response to double-stranded breaks (DSBs), RIF1 functions in the ATM and ATR mediated response to DNA damage. RIF1 foci formation in response to DNA damage is completely dependent on ATM.

Gene ID: 55183

NCBI Accession: NP_060621

UniProt: Q5UIP0

Pathways: Stem Cell Maintenance