RIF1 antibody (AA 1425-1450)

Catalog No. ABIN7454645

Product Details anti-RIF1 Antibody

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Binding Specificity: AA 1425-1450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-RIF1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1425 and 1450

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RIF1

Target: RIF1 (RAP1 Interacting Factor Homolog (RIF1))

Alternative Name: RIF1 (RIF1 Products)

Synonyms: 5730435J01Rik antibody, 6530403D07Rik antibody, AU016181 antibody, AW549474 antibody, D2Ertd145e antibody, RGD1562474 antibody, fc38c03 antibody, wu:fc38c03 antibody, si:dkey-89p3.2 antibody, replication timing regulatory factor 1 antibody, RAP1 interacting factor homolog (yeast) antibody, RIF1 antibody, Rif1 antibody, rif1 antibody

Background: Background: RAP1 interacting factor (RIF1) localizes to dysfunctional telomeres and functions in the S-phase checkpoint. In response to double-stranded breaks (DSBs), RIF1 functions in the ATM and ATR mediated response to DNA damage. RIF1 foci formation in response to DNA damage is completely dependent on ATM.

Gene ID: 55183

NCBI Accession: NP_060621

UniProt: Q5UIP0

Pathways: Stem Cell Maintenance