Importin Subunit alpha-1 (KPNA2) (C-Term) antibody

Catalog No. ABIN7453571

The Rabbit Polyclonal anti-Importin Subunit alpha-1 antibody is suitable to detect Importin Subunit alpha-1 in samples from Human and Mouse. It has been validated for WB, IHC (fp) and IP.

Quick Overview for Importin Subunit alpha-1 (KPNA2) (C-Term) antibody (ABIN7453571)

Target: Importin Subunit alpha-1 (KPNA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Product Details

Binding Specificity: C-Term

Purpose: Rabbit anti-RCH1/KPNA2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 475 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: Importin Subunit alpha-1 (KPNA2)

Alternative Name: RCH1/KPNA2

Background: Background: The import of proteins from the cytoplasm to the nucleus involves docking the protein to receptors associated with the nuclear pore complex followed by translocation through the nuclear pore. RCH1 is an adaptor protein that recognizes the nuclear localization signal (NLS) on cargo and binds the karyopherin importin-beta receptor for nuclear import which is regulated by RanGTP.

Gene ID: 3838

NCBI Accession: NP_002257

UniProt: P52292