CD44 antibody (AA 692-742)

Catalog No. ABIN7453578

This anti-CD44 antibody is a Rabbit Polyclonal antibody detecting CD44 in WB, IP and IHC (fp). Suitable for Human and Mouse.

Quick Overview for CD44 antibody (AA 692-742) (ABIN7453578)

Target: CD44

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CD44 Antibody

Binding Specificity: AA 692-742

Purpose: Rabbit anti-CD44 Antibody, Affinity Purified

Predicted Reactivity: Bovine,Horse,Golden hamster

Purification: Affinity Purified

Immunogen: Between AA 692 and 742

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: Background: CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis [taken from NCBI Entrez Gene (Gene ID: 960)].

Gene ID: 960

NCBI Accession: NP_000601

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling