CNOT3 antibody (AA 525-575)

Catalog No. ABIN7453678

This Rabbit Polyclonal antibody specifically detects CNOT3 in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for CNOT3 antibody (AA 525-575) (ABIN7453678)

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CNOT3 Antibody

Binding Specificity: AA 525-575

Purpose: Rabbit anti-CNOT3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 525 and 575

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CNOT3

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Alternative Name: CNOT3

Background: Background: CNOT3 (CCR4-NOT transcription complex subunit 3) is a component of the CCR4-NOT core complex that functions as a general transcriptional regulator. In a genome-wide siRNA screen for genes essential for mouse embryonic stem cell self-renewal, CNOT3 was identified and found to co-occupy gene promoters with c-Myc and Zfx.

Gene ID: 4849

NCBI Accession: NP_055331

UniProt: O75175

Pathways: Stem Cell Maintenance