MAPKAP Kinase 5 antibody (AA 423-473)

Catalog No. ABIN7453731

The Rabbit Polyclonal anti-MAPKAP Kinase 5 antibody (ABIN7453731) specifically detects MAPKAP Kinase 5 in WB, IP and IHC (fp). The antibody is reactive with Human samples.

Quick Overview for MAPKAP Kinase 5 antibody (AA 423-473) (ABIN7453731)

Target: MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPKAP Kinase 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-MAPKAP Kinase 5 Antibody

Binding Specificity: AA 423-473

Purpose: Rabbit anti-MK5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 423 and 473

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MAPKAP Kinase 5

Target: MAPKAP Kinase 5 (MAPKAPK5) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))

Alternative Name: MK5

Background: Background: MK5 (MAP kinase-activated protein kinase 5) is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. [taken from NCBI Entrez Gene (GeneID: 8550)].

Gene ID: 8550

NCBI Accession: NP_620777

UniProt: Q8IW41

Pathways: MAPK Signaling