26S Proteasome Regulatory Subunit 8 (PSMC5) (AA 1-50) antibody

Catalog No. ABIN7453806

The Rabbit Polyclonal anti-26S Proteasome Regulatory Subunit 8 antibody (ABIN7453806) specifically detects 26S Proteasome Regulatory Subunit 8 in WB, IP and IHC (fp). The antibody is reactive with Human and Mouse samples.

Quick Overview for 26S Proteasome Regulatory Subunit 8 (PSMC5) (AA 1-50) antibody (ABIN7453806)

Target: 26S Proteasome Regulatory Subunit 8 (PSMC5)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details

Binding Specificity: AA 1-50

Purpose: Rabbit anti-TRIP1/SUG1 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Pig

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: 26S Proteasome Regulatory Subunit 8 (PSMC5)

Alternative Name: TRIP1/SUG1

Background: Background: Thyroid receptor interacting protein 1 (TRIP1) was originally identified as a protein that interacts with the thyroid receptor and is homologous to the yeast SUG1 protein, a transcriptional coactivator. It was later identified as an ATPase subunit of the 26S proteasome, a multicatalytic proteinase complex, and has also been shown to associate with nuclear receptors and transcription factors. TRIP1/SUG1 may function to regulate transcription factor abundance by targeting them for proteasome degradation.

Gene ID: 5705

NCBI Accession: NP_002796

UniProt: P62195