Recombinant IL7R antibody (AA 21-236)

Catalog No. ABIN7453897

This Rabbit Monoclonal antibody specifically detects IL7R in WB, IP and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for Recombinant IL7R antibody (AA 21-236) (ABIN7453897)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BLR177J

Product Details anti-IL7R Antibody

Binding Specificity: AA 21-236

Purpose: Rabbit anti-CD127/IL-7R alpha Recombinant Monoclonal Antibody [BLR177J]

Immunogen: residues 21-236 (ECD)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 6 μL/1 mg lysate

WB: 17:40:00

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127/IL-7R alpha

Background: Background: CD127/IL-7R alpha is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. IL7 is a hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. [taken from NCBI Entrez Gene (Gene ID: 3575)].

Gene ID: 3575

NCBI Accession: NP_002176

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size