NCOA4 antibody (AA 500-550)

Catalog No. ABIN7453907

This anti-NCOA4 antibody is a Rabbit Polyclonal antibody detecting NCOA4 in WB, IP and IHC (fp). Suitable for Human.

Quick Overview for NCOA4 antibody (AA 500-550) (ABIN7453907)

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-NCOA4 Antibody

Binding Specificity: AA 500-550

Purpose: Rabbit anti-ARA70 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 500 and 550

Isotype: IgG

Application Details

Application Notes:

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-ARA70 antibody ABIN7449969.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NCOA4

Target: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Alternative Name: ARA70

Background: Background: ARA70 (androgen receptor-associated 70) was originally identified as part of chromosomal rearrangement involving the RET proto-oncogene. It was subsequently isolated in a two-hybrid screen as a ligand-dependent associated factor of the androgen receptor (AR). In addition to functioning as a co-activator of the AR, ARA70 has been found to function as a co-activator of the vitamin D receptor, estrogen receptor, PPARalpha, and PPARgamma.

Gene ID: 8031

NCBI Accession: NP_005428

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway