BIRC6 antibody (C-Term)

Catalog No. ABIN7453916

This anti-BIRC6 antibody is a Rabbit Polyclonal antibody detecting BIRC6 in WB, IP and IHC (fp). Suitable for Human and Mouse.

Quick Overview for BIRC6 antibody (C-Term) (ABIN7453916)

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-BIRC6 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-BIRC6/Apollon Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 4775 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BIRC6

Target: BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

Alternative Name: BIRC6/Apollon

Background: Background: BIRC6/Apollon contains a baculoviral-IAP repeat (BIR) and ubiquitin-conjugating enzyme (UBC) domain and functions in the inhibition of apoptosis. BIRC6/Apollon inhibits apoptosis by ubiquitinating and promoting the proteasomal degradation of SMAC (second mitochondria-derived activator of caspase) and caspase-9.

Gene ID: 57448

NCBI Accession: NP_057336

UniProt: Q9NR09