Recombinant FAP antibody (AA 26-760)

Catalog No. ABIN7453971

This Rabbit Monoclonal antibody specifically detects FAP in WB, IHC, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for Recombinant FAP antibody (AA 26-760) (ABIN7453971)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FAP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR150J

Product Details anti-FAP Antibody

Binding Specificity: AA 26-760

Purpose: Rabbit anti-Fibroblast Activation Protein alpha/FAP Recombinant Monoclonal Antibody [BLR150J]

Immunogen: residues 26-760 (ECD)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Alternative Name: Fibroblast Activation Protein alpha/FAP

Background: Background: Fibroblast Activation Protein alpha, or FAP, is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. FAP is involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [taken from NCBI Entrez Gene (Gene ID: 2191)].

Gene ID: 2191

NCBI Accession: NP_004451

UniProt: Q12884

Pathways: Tube Formation