Recombinant NEFL antibody (AA 150-200)

Catalog No. ABIN7453980

This Rabbit Monoclonal antibody specifically detects NEFL in WB, IHC, ICC and IP. It exhibits reactivity toward Human and Rat.

Quick Overview for Recombinant NEFL antibody (AA 150-200) (ABIN7453980)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR224K

Product Details anti-NEFL Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-Neurofilament-L Recombinant Monoclonal Antibody [BLR224K]

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: Neurofilament-L

Background: Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light (L), medium (M), and heavy (H) chains. Neurofilaments are a component of the axon cytoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. Mutations in the Neurofilament-L cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. [taken from NCBI Entrez Gene (Gene ID: 4747)].

Gene ID: 4747

NCBI Accession: NP_006149

UniProt: P07196