Recombinant SIRPA antibody (AA 31-368)

Catalog No. ABIN7453985

This anti-SIRPA antibody is a Rabbit Monoclonal antibody detecting SIRPA in WB, IHC, IP and ICC. Suitable for Human.

Quick Overview for Recombinant SIRPA antibody (AA 31-368) (ABIN7453985)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SIRPA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR049F

Product Details anti-SIRPA Antibody

Binding Specificity: AA 31-368

Purpose: Rabbit anti-SIRP alpha Recombinant Monoclonal Antibody [BLR049F]

Immunogen: residues 31-368 (ECD)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Alternative Name: SIRP alpha

Background: Background: SIRP alpha is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRP alpha is a cell surface receptor for CD47 and CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. [taken from NCBI Entrez Gene (Gene ID: 140885)].

Gene ID: 140885

NCBI Accession: NP_001035111

UniProt: P78324