Recombinant CD247 antibody (C-Term)

Catalog No. ABIN7454039

The Rabbit Monoclonal anti-CD247 antibody (Clone BL-336-1B2) (ABIN7454039) specifically detects CD247 in WB, IHC, FACS, IP and IF (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant CD247 antibody (C-Term) (ABIN7454039)

Target: CD247 (CD247 Molecule (CD247))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD247 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: BL-336-1B2

Product Details anti-CD247 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-CD247/CD3Z Recombinant Monoclonal Antibody [BL-336-1B2] - BSA-Free

Purification: Purified

Immunogen: between AA 150 to 164 (C-term)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for CD247

Target: CD247 (CD247 Molecule (CD247))

Alternative Name: CD247/CD3Z

Background: T-cell surface glycoprotein CD3 zeta chain is encoded by the gene CD247, also known as CD3Z or CD3 zeta. CD247/CD3 zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response [taken from NCBI Entrez Gene (Gene ID: 919)].

Gene ID: 919

UniProt: P20963

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway