NFYC antibody (AA 408-458)

Catalog No. ABIN7454434

The Rabbit Polyclonal anti-NFYC antibody has been validated for IP and IHC (fp). It is suitable to detect NFYC in samples from Human.

Quick Overview for NFYC antibody (AA 408-458) (ABIN7454434)

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFYC antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-NFYC Antibody

Binding Specificity: AA 408-458

Purpose: Rabbit anti-NF-YC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Orangutan

Purification: Affinity Purified

Immunogen: between AA 408 and 458

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended..

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NFYC

Target: NFYC (Nuclear Transcription Factor Y, gamma (NFYC))

Alternative Name: NF-YC

Background: Background: Nuclear transcription factor Y gamma (NF-YC) is a subunit of the NF-Y heterotrimeric complex composed of NF-YA, NF-YB, and NF-YC. The NF-Y factor binds the CCAAT box with high specificity and affinity, and it is the major CCAAT-binding activator. All 3 subunits are essential for CCAAT binding. NF-Y plays a role in regulating several cell-cycle regulated genes such as CDC2, CDC25A/B/C, cyclin A2, cyclin B1/B2, and E2F1.

Gene ID: 4802

UniProt: Q13952

Pathways: Regulation of Lipid Metabolism by PPARalpha