CSNK2A1/CK II alpha antibody (AA 300-350)

Catalog No. ABIN7454514

This Rabbit Polyclonal antibody specifically detects CSNK2A1/CK II alpha in WB and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for CSNK2A1/CK II alpha antibody (AA 300-350) (ABIN7454514)

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSNK2A1/CK II alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CSNK2A1/CK II alpha Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-CKII alpha Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken,Bovine,Rabbit

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended. Use rabbit anti-CKII alpha antibody A300-198A.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CSNK2A1/CK II alpha

Target: CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))

Alternative Name: CKII alpha

Background: Background: Casein kinase II (CKII) is a serine/threonine protein kinase that is required for progression through the cell cycle but whose major functions are not clearly understood. CKII is composed of a heterotetrameric complex that includes alpha and alpha-prime catalytic subunits and a beta non-catalytic subunit. Although from independent genes, CKII alpha and CKII alpha-prime can compensate for each other for some functions. However in response to ionizing radiation (IR) damage, CKII alpha and CKII alpha-prime appear to function independently in inhibiting apoptosis signaling.

Gene ID: 1457

NCBI Accession: NP_001886

UniProt: P68400

Pathways: SARS-CoV-2 Protein Interactome