SUB1 antibody (AA 77-127)

Catalog No. ABIN7454530

The Rabbit Polyclonal anti-SUB1 antibody is suitable to detect SUB1 in samples from Human and Mouse. It has been validated for WB and IHC (fp).

Quick Overview for SUB1 antibody (AA 77-127) (ABIN7454530)

Target: SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-SUB1 Antibody

Binding Specificity: AA 77-127

Purpose: Rabbit anti-PC4 Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken,Orangutan

Purification: Affinity Purified

Immunogen: between AA 77 and 127

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended. Use rabbit anti-PC4 antibody A301-161A.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SUB1

Target: SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))

Alternative Name: PC4

Background: Background: PC4 is a multifunctional transcriptional coactivator that plays an important role in transcription, repair, and replication. PC4 interacts with general transcription factors, DNA repair factors, and mRNA processing factors to influence transcription initiation, coactivation, polyadenylation, transcription termination, and transcriptional repression. PC4 has been demonstrated to be a DNA binding protein and a bona fide component of chromatin with chromatin-compacting ability.

Gene ID: 10923

NCBI Accession: NP_006704

UniProt: P53999