Raly antibody (AA 256-306)

Catalog No. ABIN7454547

Product Details anti-Raly Antibody

Target: Raly (RALY) (RNA-binding protein Raly (RALY))

Binding Specificity: AA 256-306

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Raly antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-RALY Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 256 and 306

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended. Use rabbit anti-RALY antibody A302-069A.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Raly

Target: Raly (RALY) (RNA-binding protein Raly (RALY))

Alternative Name: RALY (RALY Products)

Synonyms: AI663842 antibody, Merc antibody, HNRPCL2 antibody, P542 antibody, zgc:103445 antibody, hnRNP-associated with lethal yellow antibody, RALY heterogeneous nuclear ribonucleoprotein antibody, Raly antibody, RALY antibody, raly antibody

Background: Background: The agouti (a) locus includes the mouse agouti gene that regulates coat color in mice by controlling the relative amount and distribution of yellow and black pigment in the coat hairs. A mutation in the agouti locus, lethal yellow (Ay), results in an all-yellow coat color along with a number of dominant pleiotropic effects such as obesity, diabetes, tumor susceptibility, and embryonic lethality in homozygotes. Molecular analysis of the Ay transcript revealed that the Ay transcript includes the coding region of the a gene but also included novel sequence. The novel sequence was found to originate from a 5'-noncoding exon of a gene that was named Raly, because it had the potential to encode an hnRNP protein that is associated with lethal yellow.

Gene ID: 22913

NCBI Accession: NP_057951

UniProt: Q9UKM9