PSMA5 antibody (AA 100-150)

Catalog No. ABIN7454554

The Rabbit Polyclonal anti-PSMA5 antibody is suitable to detect PSMA5 in samples from Human and Mouse. It has been validated for WB and IHC (fp).

Quick Overview for PSMA5 antibody (AA 100-150) (ABIN7454554)

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PSMA5 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-PSMA5 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 100 and 150

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSMA5

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Alternative Name: PSMA5

Background: Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSAM5 is member of the peptidase T1A family and is an alpha subunit of the 20S core [taken from NCBI Entrez Gene (GeneID: 5684)].

Gene ID: 5686

NCBI Accession: NP_002781

UniProt: P28066

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA