PSMA2 antibody (AA 184-234)

Catalog No. ABIN7454564

This anti-PSMA2 antibody is a Rabbit Polyclonal antibody detecting PSMA2 in WB and IHC (fp). Suitable for Human and Mouse.

Quick Overview for PSMA2 antibody (AA 184-234) (ABIN7454564)

Target: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PSMA2 Antibody

Binding Specificity: AA 184-234

Purpose: Rabbit anti-PSMA2 Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: Between AA 184 and 234

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSMA2

Target: PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

Alternative Name: PSMA2

Background: Background: Proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2) is a component of the proteasome, a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA2 is a member of the peptidase T1A family, that is a 20S core alpha subunit [taken from NCBI Entrez Gene (Gene ID: 5683)].

Gene ID: 5683

NCBI Accession: NP_002778

UniProt: P25787

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA