LARS antibody (AA 250-300)

Catalog No. ABIN7454577

This Rabbit Polyclonal antibody specifically detects LARS in WB and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for LARS antibody (AA 250-300) (ABIN7454577)

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-LARS Antibody

Binding Specificity: AA 250-300

Purpose: Rabbit anti-LARS Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 250 and 300

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LARS

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Alternative Name: LARS

Background: Background: Leucyl-tRNA synthetase (LARS) catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. LARS exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs [taken from the Universal Protein Resource (UniProt) Q9P2J5].

Gene ID: 51520

NCBI Accession: NP_064502

UniProt: Q9P2J5

Pathways: EGFR Signaling Pathway