PCCA antibody (AA 678-728)

Catalog No. ABIN7454579

The Rabbit Polyclonal anti-PCCA antibody (ABIN7454579) specifically detects PCCA in WB and IHC (fp). The antibody is reactive with Human and Mouse samples.

Quick Overview for PCCA antibody (AA 678-728) (ABIN7454579)

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCCA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PCCA Antibody

Binding Specificity: AA 678-728

Purpose: Rabbit anti-PCCA Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: Between AA 678 and 728

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PCCA

Target: PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))

Alternative Name: PCCA

Background: Background: Propionyl CoA carboxylase, alpha polypeptide (PCCA)is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA functions as the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia [taken from NCBI Entrez Gene (Gene ID: 5095)].

Gene ID: 5095

NCBI Accession: NP_000273

UniProt: P05165

Pathways: Monocarboxylic Acid Catabolic Process