GOT2 antibody (AA 380-430)

Catalog No. ABIN7454581

The Rabbit Polyclonal anti-GOT2 antibody is suitable to detect GOT2 in samples from Human and Mouse. It has been validated for WB and IHC (fp).

Quick Overview for GOT2 antibody (AA 380-430) (ABIN7454581)

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GOT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-GOT2 Antibody

Binding Specificity: AA 380-430

Purpose: Rabbit anti-GOT2 Antibody, Affinity Purified

Predicted Reactivity: Rat,X. tropicalis,Chicken,Bovine,Horse,Rabbit,Pig,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 380 and 430

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Alternative Name: GOT2

Background: Background: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology [taken from NCBI Entrez Gene (Gene ID: 2806)].

Gene ID: 2806

NCBI Accession: NP_002071

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process