Phone:: +1 877 302 8632
Fax:: +1 888 205 9894 (Toll-free)
E-Mail:: orders@antibodies-online.com

For best experience we recommend to activate Javascript in your browser.

MDC1 antibody (AA 1375-1425)

The Rabbit Polyclonal anti-MDC1 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect MDC1 in samples from Human.

Catalog No. ABIN7454587

Quick Overview for MDC1 antibody (AA 1375-1425) (ABIN7454587)

Target

See all MDC1 Antibodies

MDC1 (Mdc1 (MDC1))

Reactivity

59
44
16
12
11
2
1
1

Human

Host

Rabbit

Clonality

Polyclonal

Conjugate

28
6
6
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This MDC1 antibody is un-conjugated

Application

57
22
14
13
13
13
12
10
9
5
3
1
1
1
1

Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Discover our top product MDC1 Primary Antibody

Binding Specificity
21

15

10

8

5

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 1375-1425

Purpose

Rabbit anti-MDC1 Antibody, Affinity Purified

Predicted Reactivity

Chimpanzee

Purification

Affinity Purified

Immunogen

between AA 1375 and 1425

Isotype

IgG
anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) antibody
MDC1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 1-350) antibody
MDC1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 31-130) antibody
MDC1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody (HRP)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 HRP

anti-Mdc1 (MDC1) (N-Term) antibody (FITC)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 FITC

anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 Biotin

anti-Mdc1 (MDC1) (N-Term) antibody (PE)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 PE

anti-Mdc1 (MDC1) (N-Term) antibody (APC)
MDC1 Reactivity: Mouse WB, IF, ICC Host: Mouse Monoclonal P2B11 APC

Application Notes

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:5,000 - 1:25,000

Restrictions

For Research Use only
Concentration

1000 μg/mL

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Expiry Date

12 months
Target

MDC1 (Mdc1 (MDC1))

Alternative Name

MDC1

Background

Background: Mediator of DNA damage checkpoint protein 1 (Mdc1) is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. It is also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis [taken from the Universal Protein Resource (UniProt) Q5PSV9].

Gene ID

9656

NCBI Accession

NP_055456

UniProt

Q14676

You are here: