MTA1 antibody (AA 400-450)

Catalog No. ABIN7454605

The Rabbit Polyclonal anti-MTA1 antibody is suitable to detect MTA1 in samples from Human and Mouse. It has been validated for WB, IP and IHC (fp).

Quick Overview for MTA1 antibody (AA 400-450) (ABIN7454605)

Target: MTA1 (Metastasis Associated 1 (MTA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-MTA1 Antibody

Binding Specificity: AA 400-450

Purpose: Rabbit anti-MTA1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MTA1

Target: MTA1 (Metastasis Associated 1 (MTA1))

Alternative Name: MTA1

Background: Background: MTA1 (metastasis-associated protein 1) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA1 was identified as a factor differentially expressed in several types of metastatic carcinoma including breast cancer. MTA1 has also been demonstrated to function as a corepressor for ligand-induced estrogen receptor (ER) transactivation.

Gene ID: 9112

NCBI Accession: NP_004680

UniProt: Q13330

Pathways: Chromatin Binding