TRIM24 antibody (AA 700-750)

Catalog No. ABIN7454678

This anti-TRIM24 antibody is a Rabbit Polyclonal antibody detecting TRIM24 in WB, IP and IHC (fp). Suitable for Human and Mouse.

Quick Overview for TRIM24 antibody (AA 700-750) (ABIN7454678)

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM24 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-TRIM24 Antibody

Binding Specificity: AA 700-750

Purpose: Rabbit anti-TIF1 Alpha/TRIM24 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 700 and 750

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: TIF1 Alpha/TRIM24

Background: Background: TIF1 Alpha/TRIM24 is a member of a family of proteins that control transcription and chromatin remodeling through their interaction with transcription factors. The family of TIF1s (transcriptional intermediary factor 1) includes TIF1-alpha, TIF1-beta, and TIF1-gamma. TIF1-alpha plays an important role in development and mediates transcriptional control by interacting with the AF2 region of nuclear receptors such as estrogen, retinoic acid, and vitamin D3 receptors. TIF1-alpha has been shown to be a repressor of transcription. This transcriptional repression involves histone deacetylation and interaction with members of the heterochromatin protein 1 family.

Gene ID: 8805

NCBI Accession: NP_056989

UniProt: O15164